Chinese and foreign scientists find the nasopharyngeal carcinoma gene The onset is similar to leukemia

Chinese and foreign scientists find the nasopharyngeal carcinoma gene The onset is similar to leukemia
The centre of prevention and cure of Zhongshan University's tumour cooperates with Singaporean scientist, exchange the sense gene after discovering three pieces of new nasopharyngeal carcinoma, and confirm the antigen of human leucocyte (HLA) Gene and nasopharyngeal carcinoma have illness coming on the risk has something to do with. This achievement is issued on the international academic magazine " natural science of heredity " published on May 31. It is reported, our country is one of the countries of nasopharyngeal carcinoma with highest morbidity in the world, and South China, especially Guangdong, Guangxi and Hong Kong and other places are the high having illness coming on area, morbidity, than other high more than 100 times, area of country, so nasopharyngeal carcinoma has " cancer in Guangdong " It claims. Especially distributing nasopharyngeal carcinoma is more common than family nasopharyngeal carcinoma, account for 90% of the nasopharyngeal carcinoma patient. According to being responsible for academic leader, academician of Chinese Academy of Sciences, subsidiary tumour director's once new introduction of benefit of Zhongshan University that this project studied, as far back as 2005, this centre started the nasopharyngeal carcinoma crowd to exchange the sense gene to sift, check the work. They carry on the contrast of dividing into groups to more than 5000 nasopharyngeal carcinoma patients and more than 5000 healthy persons from South China. Discover, antigen and TNFRSF19, MDSI-EVI1, CDKN2A/2B three genes of human leucocyte are exchanging the sense gene of nasopharyngeal carcinoma, can influence the morbidity risk of nasopharyngeal carcinoma notably. Unless meanwhile, it is correlate with leukemia not to by sense gene,expert therefore judgement, the morbidity mechanisms of nasopharyngeal carcinoma and leukemia may have similar mechanism. For develop, predict nasopharyngeal carcinoma have illness coming on genetic chip of risk, improve nasopharyngeal carcinoma examining rate laid the foundation early research results this. In addition, the research has confirmed the past scientific hypothesis to a certain extent too. The expert from Singapore has proposed " One hundred crosses tribe's nasopharyngeal carcinoma origin hypothesis " ,Think the reason of the phenomenon that it causes some regional nasopharyngeal carcinoma high to have illness coming on that the gene is spread. Singapore expert point out, live before the thousands of year one hundred of the South exceed the intersection of clan and woman, carry nasopharyngeal carcinoma, exchange the intersection of sense and gene in China, via marry nasopharyngeal carcinoma, exchange the sense gene, carry by crowd of Guangdong, east African, Arab and other places, later, these people migrated from different routes to Southeast Asia, Oceania, Bering area. But verification of hypothesis this remain through gather and further study to other the intersection of area and loud sample abroad,etc. still. (reporter Zhang JingHua)

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