The mouths of brothers vaccine which China researches and develops independently finishes the first stage of clinical trial

The mouths of brothers vaccine which China researches and develops independently finishes the first stage of clinical trial
Beijing, May 25 (Xinhuanet) ' Reporter Zhou TingYu) The department of Beijing revitalizes biologicals Co., Ltd. to announce on the 25th, the intestinal virus 71 type ( EV71) which the company researches and develops independently Deactivate vaccine and finish the first stage of clinical trial, vaccine security observation and preliminary original result of study of immunity reveal vaccine has better security and can produce the good immunity to reply. EV71 virus mainly causes the mouths of brothers to be ill, can cause many kinds of diseases of nervous system. The intersection of brothers and mouth disease continuously high to take place in our country in recent years. Data that Ministry of Public Health announce reveal the whole country report the intersection of brothers and the intersection of mouth and disease to, have illness coming on more than 1,770,000 totally 2010, among them most serious disease case and death case are caused by EV71 virus. The whole world have, prevent from vaccine and generally acknowledged specific the intersection of treatment and medicine that EV71 infect still at present. Beijing department revitalize the intersection of biologicals and EV71 that Co., Ltd. develop deactivate vaccine take the lead in, supervise the administration bureau apply and enter the clinical trial by medicines to national food on will it be December 24 2009 Register, get permission the official written reply of the clinical trial will it be December 23 2010, and start the first stage of clinical trial formally on December 31. The first stage of clinical trial takes single centre, blind law, placebo at random to contrast the way, choose to include adult, children and infant and pre-school children amount to 168 experimenters, it is original to appraise EV71 and deactivate vaccine security and preliminary immunity in different crowds. The afternoon of May 25, the supervision of taking off the blind safe supervisory committee of data in this clinical trial of the first stage of clinical test data and Ministry of Public Health, national food medicines supervise the administration bureau, medicines examine comment centre, the intersection of Chinese and the intersection of food and medicines, assay research institute and relevant participation of expert, Center for Disease Prevention and Control of China, and witness and lay going on, revealed finally that there is not statistics difference to inoculate different dosage vaccine groups and bad reaction of the placebo control group, see, increase, inoculate the intersection of needle and time, increase, inoculate dosage, cause the intersection of bad reaction and the intersection of incidence and raise, the intersection of bad reaction and phenomenon that rank increases, indicate it is good that EV71 deactivates vaccine security and tolerance. It is reported, EV71 deactivates the second stage of clinical trial of vaccine and is expected to start during one or two months in the future, getting original immunity in vaccine and security carry on research, launch the intersection of vaccine and the intersection of immunity and permanent research; Three clinical trials will carry on the research that vaccine epidemiology protects the result especially.

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