Chinese scientist finds the liver cancer cell and evolves and moves the new route

Chinese scientist finds the liver cancer cell and evolves and moves the new route
The reporter, the research institute of genome of Beijing learns from Chinese Academy of Sciences today, have published Chinese scientist's newest progress in cancer genome research of hepatocarcinoma on " publication of institute of American Academy of Sciences " published recently: Utilize brand-new tumour to evolve and analyze the idea, can appraise out the time order produced in sudden change in the evolution takes place in tumour, key gene that and caused the cell hyperplasia of tumour and tumour shifted. This will control the new technology that tumour grows, appropriate medicine target of searching to click and establish the foundation so as to individual's medical treatment used in tumour for development. This research is and launch with letter of professor of National Taiwan University medical college Chen Ding, Chen PeiZhe,etc. together in the group by the genome chief of research institute Wu ZhongYi in Beijing of Chinese Academy of Sciences. Latest research results of the whole genome of hepatocarcinoma of first that the scientific paper delivered this time has reported the research. At present, cancer is the second leading main reason of the human death. Survival rate does not exceed 30% in 5 of hepatocarcinoma, lung cancer, cancer of the esophagus and gastric carcinoma, among them hepatocarcinoma is only 5%- 6%. Hepatocarcinoma is the third cancer killer in the world, occupy the second place in our country, the treatment of hepatocarcinoma takes surgery treatment as the core, but even excise in early days, there is half the number patient that shifts and recurs in 5 years. It is a dynamic course that tumour takes place, it is a result accumulated constantly in gene mutation, and have highly individual specificities. Cancer takes place and shifts the mechanism, individual medical means, has already become the problems of life sciences badly in need of solution in the 21st century. Researchers, through to shifting tumour and carrying on the whole gene order-checking in a case of hepatocarcinoma patient's normal position and liver, track DNA of tumour cells changes the course, and the one that appraised the gene mutation in this case and took place, successively in proper order. Though tumour cells usually accumulate hundreds and thousands of mutation in the whole genome, analyze researcher define 3 swell relevant key gene mutation rapidly with the intersection of tumour and the intersection of cell and colony through view that evolve. Past research shows, tumour is generally to develop by the offspring of the tumour cells of normal position to recur. In the research of this one, researchers recur through two the genome of tumour is found, tumour 1 is really a direct offspring of normal position cancer to recur, and recur tumour 2 is cloned by the brother of normal position cancer even more, but not the subgeneration is cloned. This means before normal position cancer is obtained ability grows fast, tumour cells have already been shifted. (Li DaQing)

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