The Chinese scientist is expected to develop the intact artificial cornea within 3 and 5 years

The Chinese scientist is expected to develop the intact artificial cornea within 3 and 5 years
In the intersection of China and marine the intersection of university and one animal lab., one black-and-white two domestic cat of color eyes limpid and transparent, observing every gesture around vigilantly, though look that have nothing different with the usual domestic cat, but it only accepts the animal that the cover is transplanted in the cornea how much it is a few in the world, this has not happened on the human body yet. The marine university researchers of China succeeded in developing the skin in the artificial cornea with using value at last after going through 9 years, the near future will be put into the clinical trial, and expected to develop the intact artificial cornea within three and five years, bring good news for about 60 million cornea disease patients in the world. The cornea is the transparent membrane located on the first floor of wall in front of the eyeball, the surface is smooth, lie in the eyeball foremost, keep in touch with the external world directly, easy to be damaged and infected, therefore cornea disease is comparatively seen more. The cornea disease can make transparent cornea present ashen muddily, prevent the light from entering eyes, cause eyesight to be fuzzy, fail, even lose one's sight. World Health Organization statistics show, nearly there are 60 million blind patients of cornea in the whole world, China nearly has 5 million people. It is the only hope that a blind patient of cornea regains one's sight that the cornea is transplanted, but the one that because donated cornea quantity is extremely limited, the cornea transfer operation which can be carried on every year in the whole country only has 3000 examples to 4000, are fewer than 1�� of the blind patient of all corneas. The beautiful introduction of Fan Ting, Vice President of institute of the marine life of marine university of China, the structure with cell is three storeys in the cornea, including cornea crust, the cover in cornea ground substance and cornea. At present, the artificial cornea has rebuilt and breaks through in the crust technically, though the skin has already trained and succeeded manually at present in the foreign cornea, but because has adopted transgenic technology, cause tumour nature potentially, it is unable to apply to clinic. The seminar that Fan TingJun led has been devoted to since the beginning of 2002 but the cover in the medical artificial cornea is developed, and begin to carry on the cornea and transplant the test on animals such as the rabbit, domestic cat and macaque,etc. at the end of 2008. "At present, the New Zealand rabbit after the cover is transplanted in the artificial cornea, its cornea is so transparent as to already maintain for more than one year. " It is said that Fan Ting is beautiful. The cornea laboratory doctor Zhao Jun of organizational project of marine university of China introduces, in the last batch of animal's tests, by July 8, 2010, the skin has already maintained New Zealand rabbit's cornea for transparent 391 days in artificial corneas transplanted, maintain domestic cat's cornea for transparent 209 days, maintain macaque's cornea for transparent 119 days. How to obtain a large number of normal cornea seed cells of structure and function outside body and how to develop and select the carrier support material with good biological compatibility, it has been the difficult point that the artificial cornea is being studied all the time. The marine university scientific research personnel of China pass the scientific research and key research project tackling, utilize decoration amnion of upper cortex as the support finally, train cornea seed cells under appropriate temperature and cultivation condition, and succeed in animal's test. The reporter sees on the achievement assay certificate of State Science and Technology Commission, expert that Ministry of Education organize think the technology setting-up transfer to, dye, have, cause the intersection of people and cornea endothelial cell department of tumour for the first time in the world, propose launching clinical previous experimental study as soon as possible, will put into clinical practice as soon as possible. At present, have already finished the construction of the workshop of the third type medical equipment by cooperating with bright biotechnology Co., Ltd. of space of Qingdao in the key laboratory of organizational project of Chinese marine university cornea, and obtained the third kind and planted the production licence which enter material and artificial organs, have produced and made good preparations for the leather industrialization in people's cornea of organizational project. This laboratory still cooperates with white biological engineering Co., Ltd. in Qingdao, begin to be devoted to the manufacture research of the intact artificial cornea, has already succeeded in rebuilding out the cover on the artificial cornea, plan to produce the intact artificial cornea and finish animal's transplanting the experiment from three years to five years. (reporter XuDong Xu Bing Zhang)

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