Macrobiotic explored secrets of Yongfu of township Guangxi in China - centenarian has macrobiotic genes

Macrobiotic explored secrets of Yongfu of township Guangxi in China - centenarian has macrobiotic genes
China's pattern against old and feeble research In all 15s at present of China " The macrobiotic township " China, Guangxi Yongfu elect sample that system investigates as the intersection of geriatrics and research institution of China. Macrobiotic the people in Yongfu, benefit from the unique natural environment, relate to locals' hereditary quality too. But the study on long-lived old man in Yongfu, it is a epitome of China's anti-aging scientific research Located in BJ Hospital of the flourishing area in the capital and offer medical treatment service for advanced crowd of China, seek in the outlying mountain area beyond going 2000 kilometers " The macrobiotic township " Secret. For over ten years, such work experience lets 56 -year-old Yang Ze have a kind of " pass through " Feeling. The Deputy Director of research institute of geriatrics of this Ministry of Public Health says with deep feeling, " instruments of different medicines and advanced persons prop up some people's reliance to eighty or ninety years old, other people in pure nature to live to the age of 90 naturally in the arduous environment even, 100 year old, the quality that these two kinds of states make the life has essential distinction. " The large road No. 1 of China of Dongdan of Beijing, cold Curry of two storeys of underground for a building of BJ Hospital, preserving more than 300 copies of complexion from the long-lived old man's blood sample. They are valuable materials which carry on scientific research, more than 200 samples among them collect in Guangxi Yongfu county, more than other 100 parts collect in another macrobiotic township Palestinian horse of Guangxi. Macrobiotic passwords contained really make people curious in these ice-cold glass tubes, but those tough and tensile and lasting lives let people sigh with deep feeling too. Yang Ze says, " as a medical researcher, whenever I saw those centenarians, experience the life's own strength. " In 2007, the Guangxi Zhuang Autonomous Region Yongfu county is awarded to the first batch of " macrobiotic townships of China " by Chinese Gerontological Society Title. Also from that time, Yang Ze leads his group, begins to launch studying to the long-lived crowd in Yongfu. Here becomes him right " The macrobiotic township of the world " The Palestinian horse carries on another research base after long-term research. The content with one's lot one is happy, longevity of the often happy one The intersection of Guangxi and the intersection of Yongfu and the intersection of county and the intersection of Longjiang and the intersection of township and the intersection of dragon and mountain village, thank flowing water in front of the old yuans of door while being 102 -year-old, lean against the green hill. Enter the door, meet a " middle-aged person " glowing with health ,In fact he has been already more than 60 years old this year, it is the second son counted backwards of the centenarian's. Old man have 8 children in all, 5 generations and hall now. The eldest daughter is nowadays 81 years old too, and the son of minimum is 50 years old, and a grandson of the old man's is of the same age. Thank old yuans of very much healthy straight health, the ability to move around is nimble, cook, sweep the floor at ordinary times, plant the vegetables, also take the dish to the country fair to sell choosing the load everyday when 99 years old. Speak room, she turn round, get guest candy, bystander afraid of her trip over by the little stool set free behind, just wanted to support with one's hand in the past, but saw her step gently once lifting the leg. According to international standard, old man over the 90 call longevity, 80 year old ask advanced age, calculate for old age over 65. Yang Ze points out, the health of the long-lived old man is generally very healthy, seldom has disease at ordinary times. What it is eaten that what asking to them has any macrobiotic secret, all say " to want to eat, sleep on time, go to bed early and get up early " ,The same as ordinary person. Some Chinese Methuselah has one's own unique habits and customs, for example someone only drinks the well water fetched directly, have never drunk the boiled water. Visit the long-lived old man from house to house, it is a tedious work hard. So study the group besides first 5 people that Ze Yang lead, they also draw support from locality, cooperate with the bank hospital of river of Nanning of Guangxi and county government of Yongfu. The number of people of participating in field investigation amounts to 34. In the subject, they have used the research approaches of many kinds of disciplines such as sociology, psychology, medical science, biology and science of heredity. Research has indicated already, the human body is normal to need to absorb 1500 calories of heat at least every day, and according to investigation of pool Yang, long-lived the old men of Yongfu live a poverty life mostly when being young, having eaten much bitterness, the eating habit is partial and light too at ordinary times, seldom eat the meat. Their daily average takes in heat only 1440 is nipped; It take in heat at 1:0. 9983,last balance between revenue and expenditure basically. Long-lived old man's overwhelming majority of Yongfu is all women. A common point of theirs is, the last child is relatively late when bearing time. For example already 50 year old thank old yuans of son to give birth to minimum. It contributes to slowing aging late that long-term low heat takes in and bears, this is an existing final conclusion of international scientific circles. But the intersection of Yongfu and at the age of one hundred years old long-lived secret of the old men moreover seem - -Thank old yuan have one hobby, like, listen to one of locality let " adopt, transfer " Folk song. Her bedside, is showing a pile of old tapes, and a portable recorder bought while selling dishes on the country fair two years ago. Every night, she wants to hear for a moment and adopt and adjust falling asleep. In Yang Ze's research, once made and compared and analysed optimistic index and psychology of long-lived old man and more than 2000 old men in Beijing area in Yongfu. Found finally, in Yongfu, the larger the more optimistic age is, the psychology of the long-lived old man was very gentle, and better than with the psychological condition of the middle-aged person of the area. In Beijing area, the old man's relation between optimistic index and age is in order to shoulder relevantly, the larger age is, the smaller the optimistic index is. It is the oldest elderly person for whom a birthday celebration is being held in Yongfu county at present that one hundred 107 -year-old longevity residents of village of longevity city of garrison post are old and always green. Covered with wrinkles but still delicate and pretty faces and have from old men, can find out her young graceful bearing. On the old always green family Chiang Kai-shek's desk in the hall, are showing a black-and-white photograph. The man with handsome appearance is her husband that year in the photograph. Talk about him, it is shy to show a silk unexpectedly on the old man's face, say: "He was the most handsome man in the whole town that year. " In fact, the old man's life is very bumpy, especially lost husband and son when she is 70 years old, but she rebestirs soon. Seem in pool Yang, some negative experiences have brought sad memory to the old men, but let them realize the meaning of living on. "We find in the visit, some old men even have no concept to the money, on the issue to let alone worried about and was badly paid. They do not pursue the material life, perfectly contented if can eat one's fill and wear warm clothes, this is that contentment brings happiness. " The water and soil contain Longjiang township where the macrobiotic factor goes from Yongfu county town northernmost, along river adverse current, hills are green and waters are clear all the way. " the longevity of good fortune is done " in the county Deputy Director Zhao XiuYu explains to the " Chinese Newsweek " reporter, the mountain within the territory of Yongfu is different from other places, present " Yangshan " (namely the stone mountain) With " Yinshan Mountains " (namely the soil mountain) Interweave and is distributed. This kind of natural environment " The negative and positive is balanced " ,Also regarded as one of the macrobiotic secrets by locals. Since 2006, the locality holds " longevity festival of the good fortune " every year The activity, and establish the permanent establishment - -Longevity of good fortune The office of Organizing Committee of festival, are abbreviated as the longevity of good fortune and run, is responsible for activity and daily relevant affairs. The geographical condition of Yongfu really has a distinctive quality. According to a main fact of county CPPCC? Does �� garden Bian call mast Sao �� and closely question She's razor clam's daughter-in-law to cover? 4 37 - the intersection of 25 and area during the 26, most place the intersection of desert and climate, it is difficult for young grass not to born, uninhabited, and is only in with Yongfu of the latitude, precipitation of the whole year is more than 2000 millimetres, the coverage rate of forest is up to 74.1%, the domestic trees grow green and fresh, there is no severe cold in winter, there is no heat in summer. " longevity culture will of good fortune of Yongfu " published in 2007 is recorded, because the vegetation is luxuriant, pollute it little, the negative oxygen ion content is very high in the air in Yongfu, the content of negative oxygen ion is equivalent to more than 1800 times, 3100 times of Pearl River Delta area of the Changjiang Delta area in west rivers valley per cubic meter of air. Because mountain foggy and many at the same time, here little than plain sunshine time, sunshine percentage only 32%. Once experts pointed out, because the local was influenced by solar radiation less, cause situation of senilis even than plain little, this is favorable to one of the macrobiotic factors too. And the growth of arhat fruit is the best identification of this unique geographical condition even more. Medical research indicates, the arhat fruit includes many kinds of vitamin and amino acids, have function of cleaning the breath and relieving cough, lowering fat of blood, blood pressure. In addition, are also rich in a famous and precious scarce material - -Sweet glucoside, its sugariness is more than 300 times of cane sugar, but heat nearly equals zero, is especially suitable for diabetes and obesity patient. So, since ancient times, the arhat fruit is praised as " eastern supernatural fruit " " macrobiotic fruit " ,It is the past dynasties tribute of imperial court. But arhat requirement for growth environment very much harsh fruit have, yellow pool is managed and introduced, it is great and with the humid air that this kind of plant likes warm, short sunshine, diurnal amplitude, avoid accumulated water, afraid of frost to be also high temperature resistant. Fruit of the arhats of 70% in the world is all produced in Yongfu, and mainly grow in Longjiang township. 2008, geographical science and resource researcher and king of research institute of Chinese Academy of Sciences once did the scientific investigation to several more villages and towns of long-lived old man in Yongfu on May Day. Found finally, contain rich amount of beneficial many kinds of microelements to human body in the local drinking watered. And according to releasing some to measure, selenium content in the soil of Yongfu is 1.1 milligrams per kilogram, it is 3.8 times that of national average, can call the selenium rich soil. "In a word, the water and soil are good here! " Yellow pool is managing the strip several to say getting purpose. The centenarian's macrobiotic genetic study on special long-lived crowd, always investigate the important route of the human macrobiotic secret. The international natural medical association one " There are 7 centenarians in every 100,000 people " As " macrobiotic township of the world " Standard,2004, Palestinian last standard horse asserting, it and last world long-lived townships the five. China orients this standard " There are 3 in every 100,000 people " . "The longevity is not always that a factor could play a decisive role. " Scientific circles generally thinks, besides factors in many aspects such as natural environment, social economy, the contribution rate of the inherent cause to life-span accounts for about 25%. As the geriatrics researcher, Yang Ze tries hard to find, but the genetic impact on life-span. Begin from the Palestinian horse, he has insisted on such research in ten years. According to studying, though is being same and inside the province, the gene of the Palestinian horse and Yongfu, two long-lived crowds, is not the same. Palestinian horse is enclose with hills on four sides, exchange with external world extremely inconvenient, so gene relatively pure, mainly migrate for the Malaysian crowd. And Yongfu has been keeping exchanging with the external world since ancient times, the blending of the southern and northern crowd appears on the gene. According to analysis, the long-lived crowd of the area of Palestinian horse, one of the main embodiment on the gene is year there is many lipoprotein E3, proportion accounting for 80%- 90%. State the gene, E of lipoprotein, it divides into 2 - 3 - 4 to be three kind getting inferior, can delay the intersection of old age and dull-witted, the intersection of cardiovascular vessel and the intersection of disease,etc. and age of morbidity of disease while being 2 type 3 type among them, reduce the morbidity, promote the life-span to increase. And lipoprotein E gene carries the situation and is similar to Palestinian horse people in long-lived crowd of Yongfu's year, but the proportion is slightly low, only 71.6%. But another gene of the long-lived old man in Yongfu - -One time of appearance frequency of group F of genetic form of mitochondria is 1.5 times that of other age control groups. And one time of groups F of this form, can reduce the production of oxygen free radical. It is exactly one of the reasons why the human body is old and feeble that there are too much oxygen free radicals. In fact, the genetic impact on life-span of mitochondria, it is the old and feeble research focus of studying field too at present. In 2007, the gold strength of Fudan University teaches and regards another macrobiotic township Rugao of Jiangsu as the sample, have carried on research to the long-lived old man over 705 95 of locality. Found finally, in the macrobiotic group, 21.7% genetic mitochondria of long-lived crowd was D4 form time type, this proportion is well-above other age control groups. Yang Ze finds, hereditary acting on reflects on long-lived old man in Yongfu very obviously, macrobiotic a lot of Chinese Methuselah either parents, or siblings are long-lived. Macrobiotic scientific research: " have and cure the not disease " To the gene studies of the long-lived crowd, international scientific circles has been going on all the time. As far back as August of 2001, several scientific research institutions such as the children's hospital of Boston of U.S.A. united in one of the most authoritative academic periodicals of world " journal of American Academy of Sciences " Have, has reported the result of study of the genomics characteristic to brother and sister of compatriot over 137 to 90, find when being No. 4 to dye D4S1565 location, order, perhaps the long-lived gene exists. "This was a big news in scientific circles at that time, all of us inspired very much. Because researchers claim, from half to one, will analyse and explain the mystry of human macrobiotic gene completely. But nowadays passed by in 10, the result is not still within the foreseeable future. " Academician of Chinese Academy of Sciences, Peking University old and feeble director of research center virgin smooth monarch express " Chinese Newsweek ". The virgin smooth monarch does not like " Resist aging " This word is come to call his research field. "Scientific development until today, can only say ' slow aging ', want, resist, be resisted. This word by resists aginging of someone domestic and foreign now, sometimes start from the commercial purpose. " One batch is engaged in the old and feeble scholar who studies research as being domestic initially, the virgin smooth monarch thinks, the supporting with this of the country is far from enough at present, more costs of scientific research, have often flowed into for example the research to some old diseases such as hypertension, diabetes. In 1958, the animal of Chinese Academy of Sciences has established a gerontology research room, this launched the old and feeble scientific research institution that learns to study first at home. But is cancelled for some reasons soon. The virgin smooth monarch noticed while studying abroad in U.S.A. at the beginning of the eighties of last century Get old and feeble to it studies to be one focus of medical circle. Specialize in this direction after originally planning to come back home, can have to study tumour after coming back, would not change direction oldly and feebly and study after the past 10 years. It is introduced, in recent years, research institute and animal of Shanghai life of Chinese Academy of Sciences have been studying to telomere enzyme all the time. As one of the most important theories of old and feeble mechanism, the discovery of telomere enzyme person, three American scientists obtained Nobel's physiologic and medical award in 2009. And the interest which the virgin smooth monarch studies was clicked, has already turned from telomere enzyme to Sirt1, it is said this international old and feeble at present studies one of the hottest fields. Since 2000, the State Ministry of Science and Technology successively started two " 973 " regarding old and feeble mechanism is studied The project, Chinese People's Liberation Army General Hospital (301 hospitals) which serves as the chief scientist of this project Academician Chen think have in the world our country most huge crowds old; The 56 nationalities have offered abundant genetic resources; The vast territory has facilitated the enormous difference of living environments, life styles and habits and customs. These have offered unmatched conditions for studying from the whole, cell and genetic level oldly and feebly. In addition, our country's characterized Chinese medicine theory and herbal resource, have offered the valuable experience for exploring natural compound and intervening the old and feeble mechanism, contain the latent energy broken through. The old and feeble research center of Peking University that the virgin smooth monarch established is a main participant of the above-mentioned project. He finds, a kind of gene which is called p16 can inhibit cancer, but promote the old and feeble function of cell, this is a first report in the world. The virgin smooth monarch explains, some genes which control the tumour, promote the old and feeble one; But the gene slowing aging, can promote the growth of tumour. So how be affectedly bashful the sense of propriety, let the gene play a rational role, it is very difficult, so the longevity is a complicated subject. "Our country, on the basic research to old and feeble mechanism of the human body, the level has big disparity compared with foreign countries at present. But until social economy develop into certain stage, to how slow aging, lengthen the life-span, interested in people, begin to get hot to the old and feeble research that studies too. " The virgin smooth monarch thinks, " have medicine and does not cure the disease and cure the not disease " ,To old and feeble mechanism and macrobiotic pursuing of the human body, actually exactly " cure the not disease " ,The purpose is to let people always go healthily. American state-run hygiene research institute has and specializes in old and feeble National Institute on Aging (NIA) ,China does not have a similar scientific research institution yet so far. At present, the geriatrics research institute that Yang Ze belongs to is declaring, establishing the real national-level old medical center. Launching with U.S.A. NIA " The macrobiotic family " The large-scale research project is similar, Yang Ze will also focus on the domestic " macrobiotic township " continuously Research,in order to revealing it is long-lived environmental factor and hereditary for secret. Reporter / money Wei (release from Yongfu, Beijing of Guangxi)

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