China will cultivate a batch of genetic engineering pigs that can support human organ transplant

China will cultivate a batch of genetic engineering pigs that can support human organ transplant
The genetic engineering expert in Nanjing of China announced recently, a batch of transgenic pigs would be born in the second half of this year, these pigs can offer for human organ transplant and can use the organ, in order to remedy and support body shortage. The expert of Nanjing medical university says, the different kind of transplantation of pig's organ is expected to apply to the clinical experiment from two to three, it takes the organ transplanted to depend on in the size of concrete time. All professors say when being interviewed by reporter of Xinhua News Agency that the persons in charge of this research wears: "We hope to apply eyes cornea and skin of the pig to the clinical trial within about two years at first. And the large-scale organ such as heart, kidney and liver may need to spend nearly five years. " Professor Dai says, the organ of the pig needs to carry on the genetic transformation in order to adapt to the human body, and under the circumstances that the strict hygiene is controlled, they will not carry disease germs. The researcher should take out some body cells from ordinary pig first, and decorate the gene causing the human immunity to repel, decorate, transfer it to cells, let this kind of genetic replacement that has been decorated lose its original gene in the body. Professor Dai has been studying and carrying on this kind to the pig in the past ten years " The gene is struck and eliminated " ,In order to avoid transplanting the ultra acute immunity of human body caused to repel. He has published research thesis in this respect on authoritative periodical of " natural biotechnology ",etc. of " science " many times. He came back home from U.S.A. last year, the frozen cells that several ten million genes transformed the pig at the beginning of this year have already been transported to Nanjing too. Professor Dai says, his research group has already begun to be cloning this kind of gene and transforming pigs. "Our staff members will separate they and pig's mother at once after the piglet was born in, then bring them up in the aseptic environment. " "They will also quarantine through being a series of, could be applied to organ transplant. " Professor Dai's colleague Zhao Zi builds a professor to propose, as the substitute of the human organ, pig's organ is used for organ transplant being expected to reduce the expenses in the future. "For example, the cornea that a gene transforms the pig probably only needs 1500 dollars, about 10,000 yuan. However, this is only the price of a cornea, excluding the expenses of transfer operation. " Zhao Zi builds and says. Beijing the intersection of Chinese-Japan Friendship Hospital and the intersection of clinical medicine and the intersection of research institute and Lou would rather chief of institute wear all and latest research results of group appraise for China in this respect the Jin Dynasty " It is broken through that great " . He says: "The other countries have a great breakthrough in this field, some have even already been cultivated for the non-human primate to carry on the pig of organ transplant. Paces that we catch up with them too now. " Chief of institute Lou thinks, the developing direction that is the biological engineering of using animal's organ for human body's transplanting, and the pig exactly carries on the best choice of such allogenic organ transplant. In whole world especially China, wait for patient and few voluntary donation of organ transplant support body make human state of organ transplant make people's worry too much. Data reveal, in China, have 1,500,000 people wait, carry on organ transplant every year, support body only about 10,000, still less than 1% of demand. Chief of institute Lou says, lead to the fact a main reason of the enormous disparity among this kind of supply and demand is keeping the insistance of intact idea of the body to the person who dies in China's traditional culture, " and this is not ideas that can be turned back for the moment " . The scientist says a main challenge that they face now is how to make the human body not even repel the pig organ planted into moved permanently for a long time. Chief of institute Lou says: "The one that can confirm now is, the human body will not present the acute rejection after transplanting. So the key of next research is the long-term compatibility. " He still points out, before implementing the clinical experiment, needed to build the good cultivation base, try to cultivate hundreds of this kind of genes and transform pigs in one year. But meanwhile, some doctors express their worry. They think in theory feasible to represent, face, will certainly succeed in while being in bed. Hospital doctor Ding YiTao of Nanjing drum-tower points out: "Though in theory, can solve the problem that the human body repels while striking and getting rid of the relevant gene, have, admit human body and animal still different, moreover experiment successful on monkey, can succeed too on people. " In addition, he has also proposed the doubt: "Will they bring unknown virus and disease to human body? " (Wang AiHua Deng Min Kong LingKun)

|