Why do some influenza patients have heavy condition

Why do some influenza patients have heavy condition
Washington, May 4 (Xinhua) ' Reporter Ren HaiJun) Some countries are wreaking havoc in first type H1N1 influenza, but some patients' condition is obviously more serious than that of other patients. American researchers infer, one of its reasons may be that influenza virus will make some patients' function during relatively long time of immune system not normal, thus apt to infect other pathogen, make these people suffer from more serious diseases such as pneumonia,etc.. This research is taken the lead in finishing by Philadelphia allergic and immune directors of department of the Chinese Academy of Sciences Catherine and Sulivan of children's hospital of U.S.A., the research results are published on the network edition of " biological magazine of leucocyte " on May 4. Researchers have investigated the cell factor level in some pediatrics patient who suffer from severe influenza blood plasma. The cell factor is that one kind can transmit information, protein or small molecule polypeptide with immune regulating function among cells. Find though above-mentioned the intersection of patient and cell factor level in the blood plasma rise to some extent finally, but the response of toll one kind of receptors reduce to some extent in their body. Toll one kind of receptors is the important receptor of the inborn immune system, can discern different pathogen, and activate fast congenital immunoreaction when the bacterium invades. In addition it can also regulate the intersection of acquired character and immunity, connect inborn immunity and the intersection of acquired character and immune bridge. Researchers infer, toll a kind of receptor activity reduces to lead to the fact some influenza patient immune system functions are not normal, thus has offered more opportunities that infected twice. Sulivan says, this research contributes to explaining why the infeted of some first type H1N1 influenza virus only demonstrate cold symptom, other patients are badly sick even gets killed; Also can explain why is in the children dying because of influenza, 1/4 of the people actually died in the bacterial infection. Comment in associate editor John's favor of " biological magazine of leucocyte ", though the mankind has made enormous progress in medical science in near these decades, but influenza virus has been that it is threatened that one has been enormous all the time. This new research makes people go still one step further to find out about influenza, will contribute to taking the effective treatment measure.

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