Sino-America scientist's joint study obtain the break-through Find and measure the new law of infertility
On July 20, American Science releases the latest research results of medical science of a transformation through the teleconference: " the sperm wraps up the membrane and can help to explain sterility of a lot of obscure men at present to lack " . The group that this research is composed of 13 scientists of organizations such as Davies branch school and Anhui medical university, biomedical research institute of Anhui Province of University of California,etc. finishes, having opened up the new route in order to measure and treat infertile sterile married couple, it is a great breakthrough of this field. " plans of a thousand people " The country specially engages 4 Chinese scientists such as the expert Professor Xu XiPing and launches this joint study for 18 years, this great scientific and technical result indicates our country has already reached the advanced international standards in this research field. It is in the world about 10% suffer from by sterilities infertile by married couple of 15%,lack sperm or shape, quality is problematic can only explanation a among them some case. This discovers, it is the new reason causing men to be sterile that the sperm wraps up the membrane and lacks. "This discovery lets scientists so excited as to nearly faint. " One of the authors of this research report, little biologist of Davies branch school of University of California check Reis and Bevans says at the teleconference. This kind of sperm wrapped up the membrane and lacked and was caused by the gene mutation of a kind of protein. The gene is encoded into protein of the �� defence 126, wraps up on the surface of the sperm, and help sperms to penetrate women's uterus mucus. If the intersection of man and gene this take place mutation, become and DEFB126 lack normal �� defence 126, then its sperm is very difficult to swim across the mucus, joins with the ovum finally. If gene mutation this have two duplicate mean sperm can't produce the intersection of bag and membrane. This DEFB126 gene mutation can explain a lot infertile sterile cases not solved now. The intersection of research and author of thesis one of this, build auspicious to consult and say at the teleconference on the same day by the intersection of branch school and Professor, Davies of University of California: "If men lack DEFB normal gene, married couple's probability unable to be pregnant will increase notably. " The research is found after testing 500 pairs of Chinese newly-married couple, if men lack 126 genes of ��'s defence and carry the mutant DEFB126 gene and will lead to the fact fecundity drops, though these persons who carry do not have reproduction defect which people think in a normal sense, for example the sperm amount is insufficient and sperm's adaptability is bad. The wife of the men of the gene feels a pain more pregnant even more than other married couple that carry the �� defence 126 and make a variation, 30% are difficult to bear. Though it is the Chinese married couple to study samples, in every crowd that researchers found they measured, 1/5 of the men all carry and should make a variation the gene, including Japan, Africa, European and California, U.S.A. man. Xu XiPing serving as the professor of research institute of the biological medicine of Shenzhen University says, the sperm which lacks membrane of bag does not always fail, also need to further observe its impact on whole male sterility in more extensive crowd now. In addition, even to the married couple that can be pregnant, it has offered one to observation chance on influence of the incident of terminal of anaphase healthy reproduction. It is very easy to carry on DEFB126 testing and diagnosis to men, have important clinical meanings, for treat, carry DEFB make a variation man of gene offer perhaps, this it is healthy reproduction that transform an achievement of milestone of medical research. This research results are published on the " science - transform medical science " magazine on July 20 and key recommendation. (reporter Wang Hui)
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