Saturday, May 12, 2012

It is pulmonary embolism " Rectify name "

It is pulmonary embolism " Rectify name "
The intersection of staff reporter and good the intersection of reporter and Wu YuHua Tan In medical textbook more than ten years ago, pulmonary embolism disease lead one rarely as one only still. Now, " pulmonary embolism is disease that a kind of common disease, frequently-occurring disease and danger are serious " Have already become the common understanding of the medical circle. Research project team led by subsidiary Beijing Chaoyang hospital Professor Wang Chen of Capital University of Medical Sciences and cardiovascular disease hospital Professor Cheng XianSheng outside the mound of Chinese Academy of Medical Sciences,etc., it is exactly pulmonary embolism " Rectify name " Experience personally and witness person. Through untiring efforts of decades such as them, domestic hospital pulmonary embolism make a diagnosis and give treatment the example is counted and increased notably in recent years, some hospitals diagnose every year the case of pulmonary embolism is counted and risen to several hundred from one or two, pulmonary embolism patient's case fatality rate drops from 24% to 9% in hospital. The relevant scientific findings of project team win the second prize of National Prize for Progress in Science and Technology of 2008. The lung is one " The child who will not cry " Pulmonary embolism make a diagnosis and give treatment consciousness demand urgently, improve time Wang, say lower extremities once dark intravenous thrombus loss, will enter the lung artery with the blood circulation, will lead to the fact pulmonary embolism happens, this is the main reason that pulmonary embolism happen. For define clinical situation of having illness coming on, project team in hospital to the intersection of brain and apoplexy patient, the intersection of ICU and the intersection of patient,etc. and different crowd carry on dark morbidity of phlebothrombosis investigate, the investigation result reveals the morbidity of deep phlebothrombosis of our country is not lower than that of foreign countries. A frequently-occurring disease in fact, why leave the impression of the disease rarely on somebody? Wang Chen says, the main reason is that detection rate of pulmonary embolism, finding rate are too low, the leaking, misdiagnosing rate is up to 80%-90%. Symptom of pulmonary embolism lacks the specificity. "It is a characteristic of pulmonary embolism without characteristic. " Wang Chen says, ten points of " conceal " of morbidity of pulmonary embolism ,Very easy other cardiovascular disease obscure, many patient might have obviously uncomfortable to faint faint, shock suddenly have illness coming on, the doctor is very easy to misdiagnose, leak and examine. On the other hand, " disguise " having illness coming on because of pulmonary embolism ,The patient is difficult to go to a doctor in time. As the saying goes, the child who will cry has milk to eat, but the lung is a " child who will not cry " . The heart is ischemic slightly, the feeling that it is uncomfortable in chest that people have at once, the chest aches, will make a diagnosis and give treatment in time immediately. And even lung blood vessel presents thromboembolism of large area, the patient may not have obvious symptoms, but there is not symptom that does not mean the condition is not serious, pulmonary embolism of large area is very apt to result in fainting, shock, even die suddenly. The case fatality rate of pulmonary embolism is the same as myocardium infarction, the serious disease pulmonary embolism patient, like not treating and curing in time, mortality is about 30%. "Consider carefully, what a bloody figure this is. " In order to improve diagnosis consciousness and competence of making a diagnosis to pulmonary embolism of medical circle of our country fundamentally, the project team holds pulmonary embolism academic meeting, thematic lecture and more than one hundred times of study class actively, upgrade idea of medical worker, raise level of understanding in pulmonary embolism, train student exceed people Wan. The project team still unites 205 hospitals in the whole country and establishes and cooperates the group, carry on the technological cooperation and tackle key problems, form national pulmonary embolism and prevent and cure the network effectively, cultivate the whole country and a plurality of regional pulmonary embolism standardizations and make a diagnosis in the demonstration training center. At the beginning of what the project is started, someone is afraid too whether there can be so many pulmonary embolism patients. And when the project is summarized, a doctor coming from group's hospital of some cooperation of Shanxi says with deep feeling: "After you have diagnosed pulmonary embolism of first, you will find there are more and more pulmonary embolism patients. " "In the differential diagnosis of the condition, will consider at first whether it is will be pulmonary embolism or not. " Breathe and thank wooden doctor Wan for saying with the medical department of critical disease after participating in Beijing Chaoyang hospital that this subject studies. Make the first " guide of making a diagnosis to pulmonary embolism " of our country The healing solution is suitable for the national conditions Except exist to the morbidity of pulmonary embolism for a long time " Misunderstand " Outside, our country lacks the norm to the making a diagnosis and giving treatment of pulmonary embolism too. For example some doctors make a diagnosis and give treatment pulmonary embolism will use and dissolve the bolt treatment soon, or use the anticoagulatory medicine, but the dosage is not up to standard of, difficult in order to treat effectively in time. For this reason, project team make first of our country on 2001 <>Until " whether pulmonary embolism - dark phlebothrombosis image learn and check the operational procedure". In treating, according to following the medical research of the card strictly on a large scale, the project team has appraised urine kinase and recombination organizing type of different schemes finely and dissolved zymogen activator (rt-PA) Dissolve bolt result,there are great innovation on that last healing solution. Discover, as to the Chinese crowd, rt-PA50 milligram has good clinical curative effect, and then rise to 100 milligrams of its curative effect and does not increase, has increased the incidence bleeding instead. Therefore confirm, are lower than rt-PA50 milligram of half the American-European consumption for the suitable for dissolving the bolt scheming of compatriots. Turning down the dosage not only can keep the same therapeutic effect, reduced the side effect, but also lightened the patient's financial burden at the same time. Wang Chen says, the project team still follows the medical research approach of the card on large scale, has compared ordinary Heparin with the anticoagulation therapeutic effect of low molecular Heparin, and compared its economics index of hygiene with, has proposed being suitable for the anticoagulation healing solutions of the national conditions. Besides drug therapy, the project team has also launched in the artery thrombus of lung the membrane peels the thromboembolism artery high pressure of lung of chronic thrombus of skill treatment, the mortality of operation is only 5.7%, reach the international most advanced level. Launch the intersection of lung and the intersection of artery and conduit get involved, treat, efficient to up to 95%. Announce compatriot have illness coming on characteristic study, step into international advanced the intersection of ranks and time Wang, think, improve the consciousness of making a diagnosis, need propagating extensively, need speaking with the fact even more, obtaining becoming the most effective evidence of a series of scientific findings. It is the constant deepening studying that has driven educational circles and public pulmonary embolism to prevent and cure the constant enhancement of consciousness. The looking forward method of before for the first time of project team has obtained the medical base-line materials of description of compatriot's pulmonary embolism of big sample, having set up the clinical database of intact compatriot's pulmonary embolism, including clinical research database and hereditary resource database. Described the clinical manifestation of compatriot's pulmonary embolism accurately at the same time. Diagnosed the main basis having difficulty in breathing, spitting blood, chest of pulmonary embolism ached in the past " Three is united and solicited " ,And the project team is prospective through a large number of discover, compatriot's pulmonary embolism regards having difficulty in breathing as main symptom, have offered for clinical diagnosis and consulted importantly. The project team studies and discovers about hereditary epidemiology of molecule that the Hans of our country carry on, the Hans are different from exchanging the bolt mechanism of white race; Cardiovascular the intersection of disease and hospital finish 110 big pulmonary embolism corpse of sample examine pathology to study outside the the intersection of Chinese Academy of Medical Sciences and mound, have announced the characteristic that compatriot's pulmonary embolism patho-anatomy changes. The project team studies serial basic experiments, including the setting-up of different animal's models of pulmonary embolism, on this basis, have explored CT and MR to pulmonary embolism around the experiment type Diagnosis function,it is last the experiment researches of treatment and mechanism not to last pulmonary embolism, to having important suggestion meanings clinically.

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