China succeeds in developing and measures reagent box to Escherichia coli of Germany's epidemic situation

China succeeds in developing and measures reagent box to Escherichia coli of Germany's epidemic situation
To the intersection of German and the intersection of Escherichia coli and epidemic situation, China old research of gene group study into the new development and then will it be night June 7, have announced third of the intact atlas of genome of Escherichia coli which contain data of checking order newly, and diagnosis reagent box that cooperates in developing this Escherichia coli with the military microbial epidemic disease research institute of academy of medical sciences, will offer and measure the method detail of the experiment and necessary to guide the thing array information free, offer support for that the condition diagnosis in the global range, epidemic situation monitor investigating with the pollution sources. German Escherichia coli epidemic situation breaks out since mid-May, has already caused endangering to Germany's public health seriously, the epidemic situation is spreading to all parts of Europe successively too. Global scientific research workers are utilizing array information of genome of this Escherichia coli that the big genetic research institute of China of Shenzhen announces before to study actively. The whole genome equipment result released newly this time, intact (intact degree> 99%) than edition released before And the equipment mistake that may appear before revising. The analysis on genome array of this edition has verified too this Escherichia coli contains, comes from enterorrhagia Escherichia coli (EHEC) With sticking Escherichia coli (EAEC) of intestines Pathogenic gene. On the basis of the finding before this, China is big the gene has been directed with the scientific research personnel of the military microbial epidemic disease research institute of academy of medical sciences against the research and development of the diagnosis reagent box of this Escherichia coli rapidly. And verified and finished PCR that can measure the bacterial strain of this Escherichia coli fast and diagnosed the scheme. This diagnostic method mainly guides the increase of the thing through two pairs of specificities, and appraise out and bind with sticking and bleeding relevant gene. This method can offer and diagnose the result in 2- 3 hours after receiving samples, it plays a important role in the fact that the epidemic situation control the detection with the pathogenic germ. China is big the gene carries on data analysis and experiment test to sensitivity and specificity of reagent box, the identification should find the scheme has high specificities. It shows too that the sensitivity experiment measures the result, this method is low to about a cover grams (each of defeat 12 of 10) in DNA density Reaction system in still can detect this bacterial strain. More verification is tested and continued launching this week. (light beautiful Liu ChuanShu of roof beam)

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