The renewal of preventing and curing the guide of hepatitis B: Change dressings easy to lead to the fact, able to bear medicines blindly
It is very harmful to look at very beautiful hepatitis B and virus, only by insisting on treating for a long time can it control effectively. Pursue /canopy intention After five year, " chronic hepatitis B prevent and cure guide " can upgrade finally. December 10, the 2010 version " guide " (hereafter referred to as the new " guide ") Release in Beijing. Looks on 2005 first " guide " relatively ' Hereafter referred to as the old " guide ") ,The new " guide " has put forward more normal and more concrete requirement too in medicine for treatment of hepatitis B. The vaccine dosage of the keyword varies with each individual and keeps the same with old edition needle time, the new edition " guide " still puts emphasis on inoculating vaccine of hepatitis B and preventing HBV (B-mode hepatitis virus) The most effective method to infect. However, on the recommendation dosage of inoculating vaccine, distinguish to some extent because of different crowds this time. Credit of hepatopathy of Chinese Medical Association is known to General Board Jia JiDong and introduced, especially emphasize the dosage of time and injection that the first needle of vaccine of hepatitis B injects in the new " guide ". He say, baby should in born 24 hours (had better after born in 12 hours) Accept the hepatitis B vaccine injection of dosage of 10 micrograms. So can be in order to improve the result which blocks mother-to-baby transmission notably. And hepatitis B vaccine that baby's first needle injects is mostly 5 micrograms before this. In addition, the new " guide " also points out, the children not inoculating vaccine of hepatitis B to neonatal period should reseed. The adult inoculates vaccine of hepatitis B, should choose 20 micrograms on the dosage. The intersection of " the guide " and newer part this have getting low to immunological function or have no persons who reply to vaccine of hepatitis B ' Do not produce antibodies) Should increase inoculation dosage and needle time of vaccine, recommend the dosage as 60 micrograms / needle. As for the needle time, the expert points out, having no persons who reply to 3 stitches of immune procedures can inoculate 3 more stitches. Jia JiDong says, generally speaking, the protection result with the person who replies antibody can last 12 years at least after inoculating vaccine of hepatitis B, so common people do not need to monitor or strengthen the immunity, but to the high-risk group such as the low one of immunological function, other wounded incident, still propose monitoring regularly, can strengthen the immunity if necessary. Keyword park medicine park the intersection of medicine and the intersection of standard and more strictly old " guide ", establish the fundamental position against virus treatment. Have approved extensively in the antiviral treatment has been clinical at chronic hepatitis B over the past 5 years, prevent and cure the overall level after improving hepatitis B of our country. About treating the part, the new guide continues emphasizing the function against virus treatment, but put emphasis on adapting to the card further, define the long-term therapeutic concept further. " compared with old edition, the antiviral and therapeutic general adaptation card is basically unanimous for the guide that Jia JiDong introduces, new ", so long as adapt to the card and conditions permit, the antiviral treatment that is standardized on answering, getting the obvious fiber out of meanwhile takes to go on antivirally and treat. In the new " the guide " about antiviral the intersection of treatment and nucleoside in the medicine ' Acid) Have made corresponding modification too in course of treatment and suspending the medicine standard of the analog. JiDong Jia introduce, make by the intersection of Lammi and, good fortune of A Germany ester, kindness Wei and until than longer courses of treatment that make for the intersection of card and Wei, reaching HBVDNA (DNA of hepatitis B and virus, namely hepatitis B virus gene) Less than measuring lower limit, ALT (third amino acid transaminase) After being normal, consolidate one and a half years (pass at least check 3 times, at intervals of 6 months each time) more at least Maitain unchanged still and total course of treatment, at least already for two and a half years person, Fang Ke considers parking medicines. China second army medical university hospital, Changhai of Shanghai, infect the intersection of head of the department and the intersection of plan and refined Professor Wan, point out, according to investigating, " three no " quite a few of patients exist : Namely does not stop medicines according to the standard, take medicine not according to the rule, change dressings not according to the doctor's order. Check the virus many times negatively after some patient administration, liver function is normal, medicines stop by oneself, the condition recured finally, all that has been achieved has come to nothing; Though some patients have not stopped medicines, work by fits and starts, will lead to the fact the curative effect of medicine is unstable, even jump instead the virus. The keyword selects medicine opportunity and medicine to regard medicine for treatment of hepatitis B as equally important and able to bear medicines easily, it is a thing letting the hepatitis B patient have a headache most. A lot of patient in a certain nucleoside of using ' Acid) After one kind of medicines is able to bear medicines, change to try with other similar medicines, in fact, this kind of method will possibly lead to the fact the patient appears many kinds of glucoside ' Acid) Variation one which is able to bear the medicine of kind, that is to say that is able to bear medicines to many kinds of medicines at the same time. Plan Wan say some patient hear which kind of effectual to use medicine instead by oneself right away medicine while being refined, result change dressings by oneself improve curative effect, accelerate, able to bear medicine instead, might cause the intersection of condition and the intersection of person who worsen and serious consequence. In order to standardize the antiviral treatment of hepatitis B, the new " guide " emphasizes, classify with different crowd's virus levels before treatment, monitor regularly, determine whether to adjust the healing solution or not according to replying the situation and can improve the therapeutic effect effectively. The expert introduces, the is determined as the example, choose the poor patient of virus Lammi, of Lammi at the beginning treats definitely. If the intersection of hepatitis B and virus in 10 the third power of the above, should change dressings or unite good fortune of A Germany the intersection of ester and treatment Wei in time 24 week, can prevent from being able to bear medicines effectively, improve curative effect. The expert emphasizes, it is the choices of opportunity and medicine to treat optimally, do the correct thing in correct time, offer basis for standardizing the antiviral treatment of hepatitis B. (reporter Zhu RuiJuan)
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