Traditional Chinese medicine blood must prevent and cure pyemiapyaemia mechanism announce tentatively only

Traditional Chinese medicine blood must prevent and cure pyemiapyaemia mechanism announce tentatively only
It is reported the blood of traditional Chinese medicine must be announced tentatively in the function mechanism of preventing and curing serious pyemiapyaemia of net parenteral solution, it is mainly through inhibiting the inflammation high moving rate clan albumen B1( HMGB1) of factor in later period Express, promote regulating T cells (Treg) Route of withering and dying and reducing the monocytic tissue factor and secreting etc., improve organism inflammation, immunity and blood coagulation function, block the vicious circle that inflammation reacts with the blood coagulation obstacle, preventing the occurrence of pyemiapyaemia and development. A few days ago, infected this research results of making the specialist paper in national microbial toxin and wound on academic meeting and the eighth pyemiapyaemia summit forum, studied and got by the seminar which the first affiliated hospital Professor Yao YongMing of general hospital of PLA led. Pyemiapyaemia and many organ function obstacle syndrome (MODS) caused by it ,It is one of the world difficult problems of medical field of urgent critical disease. Of our country famous the intersection of first aid and medical expert king must up to the traditional Chinese medicine blood that Professor developed net parenteral solution today, verify that can intervene the pathologic course of the serious pyemiapyaemia effectively through clinical many centre tests, but its precise function mechanism has not expounded yet. In the country " 973" Under the subsidy of project and national natural science fund, Yao YongMing scalds models to observe through the big mouse, pay the blood behind net parenteral solution, the liver, lung, kidney organize HMGB1 to express and obviously reduce, and lighten, scald, delay the intersection of person who recover and acute many organ damage effectively, the intersection of animal and survival rate raise notably. On this basis, through find, offer blood must person who regulate the intersection of T and cell wither losing rate rise notably behind the net parenteral solution with external experiment in the body they, its immunity inhibits the function from obviously lightening, must brief on the blood net parenteral solution can promote regulating T cells to wither to die, improve the animal T lymphocyte's immunoreactive state of pyemiapyaemia effectively, and then prevent the occurrence of pyemiapyaemia and MODS and development. Further research show, basic, normal, high the intersection of dosage and blood must net parenteral solution can relieve pyemiapyaemia animal blood coagulation function disorderly. (Zhang Xian cherishes)

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