Diagnose technology for the genetic chip " It is all right to restrict "

Diagnose technology for the genetic chip " It is all right to restrict "
Staff reporter Wang Dan Only need to bleed, you can foresee whether will suffer from breast cancer, hypertension, Al and Hamer now by oneself, even foresee whether oneself could become piano prince, dance master In recent years, numerous dozen " predict the health " , " science tells one's fortune " People's sight has poured into genetic diagnosis, genetic check organization of the banner. But, what organizations have genetic chip the legal qualification diagnosed, the final testing result can be believed, the right and wrong among them has been a question of perplexing people all the time. Not long ago, Ministry of Public Health announced the clinic allowed to launch in the first batch should use the third kind of medical technology, the genetic chip is diagnosed technology is listed. Issue subsequently <>,Define that has stipulated what hospitals, what doctors can launch this technology, attempt for this fast-developing biomedical new technology " It is all right to restrict " . Can't totally replace the clinical labs and diagnose the project " purpose to issue of " norm ", it is mainly operation and application that further standardized the genetic chip, especially establish the foundation that this technology is moved towards by the laboratory progressively clinically. " Genome director of research center, southern medical university gentle mountain range professor Zheng of South China say frankly, for a long time, because the genetic chip is diagnosed technology does not have previous standardard management, fail large-scale application at clinic still so far, have a large number of unstandard behavior that employ in the field of health care. Want to turn back this situation, will have a correct understanding on this new developing technological itself soon first of all. Gentle mountain range Zheng tell reporter whether at present, the public's understanding to genetic chip have mistaken ideas, mainly behave in two aspects: First think the genetic chip technology can diagnose all clinical diseases. "In fact, as to some infective diseases, for instance infection of hepatitis B and virus, HIV,etc., clear diagnosis that the genetic chip can make comparisons more fast, more sensitively than traditional laboratory inspection, but change disease caused to many genes such as cancer, old and feeble, vascular disease and diabetes of the heart brain, the genetic chip can only measure the human body to its intensity of exchanging the sense at present. " Gentle mountain range Zheng say genetic chip diagnose suitable for those rely on present clinical diagnosis means still unable to make a definite diagnosis of mainly, and the patient has already had symptom or felt out of sorts subjectively, hope to pass and observe the change of genetic level, make the situation of the judgement to the health status. Say popularly, the genetic chip can not be totally replaced at present the clinical labs diagnose the project, and should be considered as the supplementary or expansion that the clinical labs diagnosed. The second misunderstanding is to think the genetic chip to diagnose technology can not still solve the practical problem at present, the fact is not like this. ", the inferior clinical or subhealthy state, when the question as to clinic, the genetic chip is diagnosed technology may offer the previous one, support to the clinical genetic analysis data that consult. " Zheng is gentle the mountain range recommend, clinical and commonly used detection means, measure the disease state already present at present, but because the genetic chip measures from the molecule level, probably find the clue the most early at disease. It is not all tertiary hospitals that can launch " the detection including gene of genetic chip is drawn ", several steps that the washing, scanning, genetic data analysis, gene of genetic chip are diagnosed,etc. after genetic mark, genetic chip are hybridized, hybridized, a bit mistake will all have a ' fatal ' impact on last testing result. " Gentle mountain range Zheng say while to clinical transformation this new developing biotechnology just because of this, analyze personnel all have extremely high, extremely tight requirements about laboratory, apparatus, technical staff, result, this characteristic has got abundant embodiment in " norm ". It is introduced, get permission to launch the genetic chip at present to diagnose the medical organization of technology not merely requires the tertiary hospital, also there should be subject of making a diagnosis of medical blood screening test lab that health authorities check and approve registration, there are laboratories related to corresponding safe grade that the sample of the bio-safety is gathered and dealt with. Meanwhile, also specialized nuclear acid of sample draws and prepares the operating room, amplifies and hybridizes the operating room, data analysis room of the genetic chip (district) with the template ,Allocate corresponding specialized instrument and equipment,etc. at the same time. Moreover, the reporter is while reading " norm ", find this technology to personnel's requirement also analogous to " harshly " . Zheng is gentle the mountain range shows, it can also be quantized that the data quality of the instrument is controllable, and people for mistake can only rely on experience for a long time accumulate and try hard to avoid skilled operation skill. "The genetic chip is diagnosed to be a new technology with extremely strong specialization. The laboratory attenbant should analyze the sample, hybridize through the molecule, confirm the existence of the purpose gene; But diagnose personnel need to analyze change and relevant data of the gene, make diagnosis, to get the health out of, consult the suggestion person who examine. " Gentle mountain range Zheng introduce, have nothing in common with each other to two requirement of person according to their working characteristics too in the " the norm ". Among them, it must be biological and medical relevant speciality, on-the-job personnel of our institute of the academic credentials above undergraduate of the university that the genetic chip measures personnel, know using operation,etc. of relevant instrument and equipment skillfully; But the genetic chip is diagnosed personnel need the working experience of the above clinic diagnosis for 8 years, have associate professor of treatment and the post qualifications of the above professional technique,etc.. In addition, " norm " requires clearly, the two should diagnose it can be on duty that it is qualified that the technological system trains and examines through the genetic chip. Ethics the intersection of norm and important gentle mountain range Zheng say frankly gene make a diagnosis technology moves towards clinical practice, the greatest difficult problems faced do not lie in technology oneself, but ethics and law. Medical in the field " Foresighted " ,When will often let people who accept detection fall into the great one puzzledly. An expert in Beijing says to the reporter, in he sifts the family of patient that finds out too while giving an interview, uneasiness that the patient demonstrates far exceeds the doctor's imagination. Some gene persons with the defect live in the fear all day, often demand to do the inspection, because they think they may suffer from cancer at any time; Some are requiring the doctor to keep secret for oneself constantly, fear one's own genetic defect will influence the marriage, afraid that will influence monobasic health. "So, say from a certain angle, the ethics norm is even more important than technology. " Mountain range introduction that Zheng is gentle, " norm " is proposed clearly, the medical organization which launches this technology needs to have genetic chip composed of respects such as medical science, law, ethics,etc. expert to diagnose technological clinical practice and ethics committee, all genetic chips are diagnosed the development of technology must be supervised and carry out by it. Moreover, diagnose result and relevant data as to the genetic chip, the medical organization should set up security system, guarantee all data only used for patient diagnosis and hospital because of raise, diagnose what competence carry on non-commercial Scientific research of sex medicine. Zheng is gentle the mountain range shows, from gene to protein because of the emergence experience of the human disease, reach cell, change of organization and then, display in the intersection of internal organs and aspect waiting for a series of complicated course finally, so, the gene changes as the most early quantitative change, the relation with disease can not be corresponded to one by one. That is to say, the result that all genes measure, is only worth consulting. So, the doctor is before adopting the genetic chip to diagnose, objective assessment and attentive matters of purpose, technological dependability, reference value, result that should tell a patient diagnoses genetic chip, and economy and psychological burden that may happen, and signed the letter of consent in the know. Chain: It means drawing cores sourly(DNA and/or RNA) in the samples of clinical patient that win that the genetic chip is diagnosed Amplify and the mark, the probe after the mark hybridizes the molecule with the genetic chip, get picture and data that the genetic chip hybridized through the genetic chip analytical instrument, analyze by the computer program, and is analyzed the above-mentioned data by the doctor with qualification and experience, give and pay a home visit and give up the whole course which consults the opinion.

|