The scientists of China and Australia find newly Malignant tumour and skin carcinoma or having new treatments

The scientists of China and Australia find newly Malignant tumour and skin carcinoma or having new treatments
The intersection of www.chinanews.com and the intersection of Hefei and October 26 cable (Yang it protects the intersection of country and Wu to be blue) The reporter interviews to learn in Chinese University of Science and Technology, are cooperated with Newcastle university Professor Zhang XuDong of Australia by the Wu 's of this school on the 26th, find a kind of small RNA149 * members participate in emergence and development of melanin tumour. It is reported the intersection of research results and expected change this skin carcinoma treats the current situation at present. Melanin tumour is commonly called as skin carcinoma, it is a kind of malignant tumour with very large with very high morbidity harmfulness. And p53 is that the most important tumours found inhibit the factor up until now, it inhibits tumour ability in the tumour cells above the 50% of mankind, but in melanin tumour, p53 does not have ability to inhibit tumour under most situations, even under some medicine function, p53 still plays a role in protecting the tumour. So, the resisting function that there are melanin tumours, the therapeutic effect is very unsatisfactory. This is " abnormal " The phenomenon is perplexing Chinese and foreign scientific research personnel for a long time. Wu remote to wait for someone, discover one call * of RNA149's little members it participates in this to be " abnormal " Phenomenon. In the intersection of melanin and tumour, adjust and control little content of member this through p53, increase, inhibit cell wither the intersection of albumen and content of Mcl-1 that die, thus make melanin tumour cells survive, this announces mechanism that melanin tumour forms. Researchers pass the analysis and research of the case sample of the clinical patient of 60 melanin tumour, also proved the content of small RNA149 * members is presented and risen notably more than the healthy person's normal organization, mean this little member can be regarded as the basis of tumour clinical diagnosis of the melanin. In addition, the little mouse experiment shows, reduces the growth that this little molecule content can obviously inhibit melanin tumour, this has offered a potential target location for treating melanin tumour, for the research and development of the clinical medicine. The expert claims, this research results may be used for improving the diagnosis of melanin tumour and treating. The relevant research results were published in the internationally famous academic periodical " publication of institute of American Academy of Sciences " not long ago Have. (End)

|