Traditional Chinese medicine injectable preparation wants science to be rational when being used The safe problem needs to strengthen and pay close attention to

Traditional Chinese medicine injectable preparation wants science to be rational when being used The safe problem needs to strengthen and pay close attention to
Summary: Traditional Chinese medicine injectable preparation is in the crossroad. Herba Houttuyniae incident, stinging five plus injectable preparation incident The traditional Chinese medicine injectable preparation bad reaction that will be sent frequently is run into " There is not traditional Chinese medicine to poison function" Masses inertia thinking,there are possible to expand in problem on security of traditional Chinese medicine injectable preparation. News traditional Chinese medicine injectable preparation of Shun net is in the crossroad. Herba Houttuyniae incident, stinging five plus injectable preparation incident The traditional Chinese medicine injectable preparation bad reaction that will be sent frequently is run into " There is not traditional Chinese medicine to poison function" Masses inertia thinking,the traditional Chinese medicine injectable preparation one security possible to expand in problem, even initiate " Whether cancel traditional Chinese medicine injectable preparation " Dispute - --Knew traditional Chinese medicine injectable preparation a few days ago correctly, Ministry of Public Health, national food medicines supervise the administration bureau, State Administration of Traditional Chinese Medicine jointly issuing " notice on further strengthening injectable preparation producing and clinical use and management of traditional Chinese medicine ". The purpose is to ensure medical security and patient's administration to be safe. The medicines supervisory system of our country is being still improved constantly, in this process, the science that the current situation that chemical medicine and traditional Chinese medicine coexisted is being supervised to medicines has been put forward, tested greatly. In near these decades, increasingly much traditional Chinese medicine injectable preparation is applied to clinic. The late, living beings with slow function utilize one degree of low grade to be insufficient after they have overcome traditional Chinese medicine and played the result, especially producing other difficult function with the substitution of dosage form of hitting medicines in rescue of the urgent critical disease. However, it is extensive day by day with employing, bad reaction and bad incident that traditional Chinese medicine injectable preparation causes increase to some extent. Some existing traditional Chinese medicine injectable preparation, it is relatively weak to develop the foundation, the production technology is defective, quality level is not high, there are potential safety hazards. So, from this year, national food medicines supervise the administration bureau appraising after going on the market to injectable preparation medicines successively. This work is not to eliminate or abolish traditional Chinese medicine injectable preparation briefly, but should improve its quality criteria, in reasonable range, let traditional Chinese medicine serve the people better safe risk control. Quality control reduces and endangers the key if the medicines bad reaction is difficult to avoid, then how does traditional Chinese medicine injectable preparation reduce the danger by quality control? In recent years, traditional Chinese medicine injectable preparation is considered to represent a modernized developing direction of traditional Chinese medicine, as the points of growth of profit of enterprises, are favored by the medical enterprise. Develop traditional Chinese medicine injectable preparation variety now, not merely a factory that make traditional Chinese medicine is interested, more Western medicine factories even foreign capitals, joint-venture pharmaceutical factory are very interested in. The expert thinks, the differentiation method of some traditional Chinese medicine injectable preparation is difficult to confirm the true and false at present, can't reach the requirement for controlling quality. The chemical composition of traditional Chinese medicine of single flavor has been already complicated enough, there is much flavour of a drug of compound traditional Chinese medicine injectable preparation, there is no flavour of a drug distinguished to increase too, bring very great difficulty to affirmation of the products. Injectable preparation pours into the body directly, its quality must insist on high-standardly. Each kind of medicine of injectable preparation makes up there must be reliable differentiation method. Without differentiation method or variety not reliable of the differentiation method, should be on the basis of appraising again, improve the science of the differentiation method, otherwise should eliminate this variety. Need to emphasize, traditional Chinese medicine injectable preparation makes up medicines should not be too many, try hard to choose two flavor carefully, should not exceed three medicines. Traditional Chinese medicine injectable preparation should be careful and complicated and apt to produce the allergic response with the injectable preparation composition of traditional Chinese medicine, want until " whether can take orally the intersection of skin and note, can the intersection of skin and note infuse " use, Principle. It wants reminds to be especially, traditional Chinese medicine injectable preparation certainly can't stay at home by oneself using. Expert say China medicine whom dosage form choose to cause factor that safe problem produce one of or not. Often present such a question in clinic: The same medicine, the patient is relatively safe while taking as decoction of medicinal ingredients, but the bad reaction appears easily while instilling, the parenteral solution incident of Herba Houttuyniae is illustrating. If product quality is examined strictly, curative effect and bad reaction are clear, dosage form is chosen rationally, traditional Chinese medicine injectable preparation can rest assured and use, and can up to the ideal result likewise. Dialectical theory should it manages to be the intersection of traditional Chinese medicine and essential part of theory, traditional Chinese medicine injectable preparation too dialectical application. Should especially be according to constructing the principle of using medicine managed dialectically, distinguish the pharmacology function concepts of function in the pharmacy of Chinese medicine and Western medicine strictly, can't use medicine blindly according to the explanation of medicines briefly. Because the traditional Chinese medicine composition is complicated, its reseach and application time that injects dosage form are relatively short, the compatibilities of traditional Chinese medicine injectable preparation and other medicines still belong to the blank of scientific research so far, so should strictly observe the medicines manual, try hard to use alone, should not mix and use with a container with other medicines. Should add some liquid, such as glucose parenteral solution, sodium chloride parenteral solution,etc. between two kinds of medicines, prevent two kinds of medicines from mixing chemical reaction in blood, prevent the bad reaction from happening. In addition, the conditional hospital should set up the intravenous medicine and dispose the centre, the pharmacist strengthens the verification of the doctor's order employed to traditional Chinese medicine injectable preparation and Western medicine injectable preparation compatibility, supervise and guide to infusion doctor through the pharmacist, the ones that reduce in the infusion are unreasonable to use medicine. Rigorously enforce usage consumption on the manual of much traditional Chinese medicine injectable preparation, mostly mark out and need to add liquid of a certain amount and can dilute application while using this medicine, until manual carry out safe, go beyond whom manual stipulate use medicine density to be apt to appear bad reaction. So should use medicine according to the manual strictly, avoid over quantity application; The course of treatment of useful medicine of traditional Chinese medicine injectable preparation, should stop medicines in time when the course of treatment finish. Should also control and instil the speed strictly at the time of the infusion, it is too fast or slow to avoid. Traditional Chinese medicine injectable preparation will lead to the fact some density of medicine is too high to instil too fast, can make the insoluble particle build up, stop up and cause dizzy, pain, stimulating dermatitis,etc. in the capillary; It is slow to instil, traditional Chinese medicine injectable preparation oxidizing, changing color, pH value easy to hydrolyze changes and causes the emergence of the bad reaction. In addition, traditional Chinese medicine variety is complicated, and different because of medicine base sources, the chemical composition, biological activity and toxicity included by it will be different to some extent, this is a reason to influence traditional Chinese medicine security directly too. Author: Sun Yong

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