Chinese scholar announces the new mechanism that the atrium quivers for the first time Have already locked the relevant target to click

Chinese scholar announces the new mechanism that the atrium quivers for the first time Have already locked the relevant target to click
From Harbin medical university " The basic research of of great heart " The scientific research group which 973 project chief scientist academician Yang BaoFeng headed, will find the clinical most common arrhythmia type for the first time in the world in the near future - -New mechanism and small nucleotide - 328 that the atrium quivers and happens adjust and control the vibrant emergence of atrium. This discovery was issued in the authoritative magazine of international cardiovascular field was " circulated" a few days ago. The seminar finds small nucleotide of vibrant patient of atrium - 328 rises notably, and raise the intensity closely related to morbidity intensity. For open small nucleotide - 328 in quiver room" The secret " ,Yang BaoFeng and seminar member tackle key problems jointly, set up particular small nucleotide of heart (1 for the first time in the world, 26,328 is inferior type) Cross and express transgenic mouse and small nucleotide function and strike and reduce mice (328 inferiorly type) ,Find small nucleotide - 328 crosses the expression the atrium that can bring out the little mouse quiver, and strike and reduce mice or transfer to small nucleotide dyed - 328 against the widowed nucleotide of justice the adenovirus in small nucleotide - 328 functions, can lighten the quiver emergence of the room. In order to further reveal the secrets small nucleotide - 328 raises and brings out the vibrant target of atrium to click, the seminar uses many kinds of experiments to prove, small nucleotide - 328 makes albumen of two genetic CACNA1Cs and CACNB1 of the code calcium passway express, and the thereupon prominent reducing of size of calcium electric current of Model L. On the contrary, inhibiting small nucleotide - 328 can reduce the quiver emergence of the room. Seminar pass a large amount of from body, in the intersection of body and experiment and clinical observation of animal, confirm small nucleotide - 328 whether atrium quiver key the intersection of adjustment and member that take place finally, understand vibrant emergence mechanism of the atrium from small nucleotide field, this molecule level, for the first time, therefore lock, can treat the intersection of room and quiver new target, order by one, vibrant to treat, focus on loud meanings to atrium, have researched and developed and established the foundation for the innovation of the biological medicine industry of the heart disease field. (the intersection of clothing and dawn the intersection of peak and beautiful cloud Li, cloud of Great Britain, Chen)

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